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Automated Bioprocess Development Facility
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The bioREACTOR® 48 from 2mag AG is a miniaturized stirred tank bioreactor system. Remarkably, 48 disposable bioreactors can operate in parallel and online measurement of DOT and pH is implemented. Thereby, each vessel has a culture volume of 8-14 mL. The bioREACTOR® is implemented into a Tecan Freedom Evo platform to automate sampling and feeding.
Various analytical measurements (e.g. optical density, glucose and acetate content among others) can be analyzed by the robot. Moreover, a flow cytometer MACSQuant (Miltenyi Biotec, Germany) measures the cell´s physical and chemical characteristics.
Finally, the data are collected and managed by a user-friendly database system.